When transitioning Mormons begin to question the validity of the Word of Wisdom, many begin to explore and experiment with previously forbidden substances. Some have positive experiences, but not all. This presentation will address substance use from a mental health perspective, addressing common pitfalls, and offering strategies for exploring the use of coffee, alcohol, cannabis, psilocybin, ayahuasca, and more. The presentation will not focus on legal issues, but rather on the medical and psychiatric applications of these substances.